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Pre- and post-analytical automation
Gain full control over your pre-analytical tasks with documented process control – standardized but flexible.
We offer dedicated platforms designed to fulfill IVD Directive 98/79/EC, with 21 CFR Part 11-compliant software, as well as open liquid handling platforms configured according to your needs.
For automation of tedious, error-prone pre-analytical tasks, Tecan offers the Fluent Mix and Pierce Workstation which eliminates the need to decap and recap tubes for pipetting and provides consistent sample mixing for standardized results.
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Tab 01 / Overview
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Pipetting precision guaranteed
When you could use an extra hand to accomplish tedious pipetting tasks faster.
Standardized. Proven. Quality.
More than 5,000 customers worldwide rely on Tecan’s Freedom EVO®-based liquid handling automation solutions for dedicated pipetting tasks in clinical laboratories, sample archiving and other, specialized liquid handling tasks.
Productivity. Simplicity. Confidence.
The Fluent® Gx is the fastest, most flexible platform Tecan’s ever made, designed specifically to meet the needs of regulated laboratories, with the advanced process security features required for applications in clinical, GMP and QC facilities.
- Made for clinical applications, the Fluent Mix and Pierce Workstation enables sample distribution from tube-to-tube or tube-to-plate through closed tube caps of common standard sample vacuum tubes. The system combines on the fly barcode reading with tube piercing and 360° tube rotation for standardized mixing.
Standardized. Proven. Quality.
More than 5,000 customers worldwide rely on Tecan’s Freedom EVO®-based liquid handling automation solutions for dedicated pipetting tasks in clinical laboratories, sample archiving and other, specialized liquid handling tasks.
- Made for clinical laboratories, the Freedom EVO Clinical provides qualified precision for pipetting from tube to tube(s), micro- or deep-well plates. The system can prepare your assays for downstream analyses, or simply create dilutions and archive samples – traceable throughout the entire process.
- Flexibility to meet changing throughput demands for post-analytical tasks, such as archiving in plates or tubes, for every common clinical sample type, with traceability.
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Tab 02 / Pre-Analytics
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Fluent Mix and Pierce Workstation
Pre-Analytics on Fluent
Don’t open, pipette and manually track another tube
- Reduce labor-intensive pre-analytical workflow steps by tube piercing instead of de-capping and re-capping. Distribute liquids from tube-to-tube or tube-to-plate.
- Rotate tubes to mix liquids, keep components in suspension (e.g. blood cells) and dissolve reagents for standardized results.
- Full workflow control for reduced risk of human error or inconsistent sample treatment.
- Cost effective, with reduced waste and consumables.
- Safe, with no exposure to potentially infectious samples.
- Made for clinical laboratories – designed to ISO 13485 and 21 CFR 820.30, enabling 21 CFR part 11 compliance.
Pipetting precision guaranteed
When you could use an extra hand to accomplish tedious pipetting tasks faster.
Made for clinical laboratories, the Freedom EVO® Clinical provides qualified precision for pipetting from tube to tube(s), micro- or deep-well plates. The system can prepare your assays for downstream analyses, or simply create dilutions and archive samples – traceable throughout the entire process.
Show moreWhen standardization is required.
- Sample archiving, transfer from tube to tube(s), 96-well and deep-well plates
- Reformatting of plates, creation of dilution series and complex pipetting patterns
- Compliant with IVD-D 98/79/EC and 21 CFR Part 11 for electronic records and signatures
- With fixed tips to save worktable space and consumables, disposable tips for delicate applications, or a combination of fixed and disposable tips to meet different application needs
Load and go sample splitting with pre-labeled secondary tubes
The instrument matches the barcodes of the primary tubes with the secondary tubes and creates a worklist without the need to configure a host connection.
Several destination tubes with the same barcode as the primary sample tube can be loaded. The instrument determines the necessary operation (dilution, splitting) via the different sections defined on the worktable.
Freedom EVO Clinical for downstream assay plate preparation
For ELISAs and parallel archive plate creation, equipped with fixed or disposable tips to prevent cross-contamination. The same instrument can be used for parallel sample distribution in plate set-up, aliquoting into pre-labeled tubes, or creation of worklists for printing out secondary tube barcode labels.
Throughput capabilities of the Freedom EVO Clinical
The Freedom EVOlution™ software automatically optimizes processing of different tasks, prepares a schedule and shows when the run has finished. The user is notified upfront of any manual interventions required during the run, such as tip or reagent reloading.
24 ELISA plates with six different assays from 352 samples can be processed in less than 2.5 hours, as shown in the example.
Plates ready for further downstream processing are easily accessible by the user while the instrument continues with its tasks. Additional samples can be processed through the instrument’s continuous loading capability.
Assured pipetting quality
| Freedom EVO Clinical 100 | 2, 4, or 8 tips | |
| Freedom EVO Clinical 150 | 4 or 8 tips | |
| Freedom EVO Clinical 200 | 8 tips |
| Fixed tips | Stainless steel, PTFE-coated | |
| Disposable tips | Tecan 200 and 1000 µl | |
| *Combine fixed and disposable tips for optimum liquid handling for your applications | ||
| Volume | 10 µl | 100 µl |
| Fixed tips | ≤ 3.5 % | ≤ 0.75 % |
| Disposable tips 200 µl | ≤ 3.5 % | ≤ 0.75 % |
| Disposable tips 1,000 µl | - | ≤ 1 % |
| Pipetting range | 10-900 µl a) | |
| Liquid level detection | Down to 50 µl of conductive liquid in round-bottom microplates | |
| Distribution | Single and multi-pipetting Parallel sample pipetting of several tests Load and go with pre-labeled secondary tubesy Load and scan for unlabeled tubes to create a worklist for barcode printing |
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| Dilution | Predispense of reagents or dilute-in-tip Common predilution for several tests per plate |
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| a) For higher maximum values liquid class might be optimized by a trained application specialist. | ||
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Tab 03 / Post-Analytics
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Automated sample archiving and retrieval
Laboratories need to be able to accommodate requests for retrospective analysis or reflex testing.
Enjoy efficient archiving with the smallest member of the Freedom EVO® family, for fast sample transfer from primary tubes to 2D barcoded cryo tubes.
The Freedom EVO 100 system allows safe and accurate collection of clinical samples, as well as easy access and retrieval when further testing is required.
Small space – 96 samples per run – high convenience.
- Automated aliquoting of laboratory-defined volumes of human plasma samples from 1D barcoded primary tubes to 2D barcoded cryotubes for archiving
- The aliquot volume can be easily adapted according to the needs of the laboratory
- Image-based, user-guided set-up
- Sample retrieval with scan and search function
- Disposable tips to eliminate cross-contamination
- A choice of two-channel pipetting for fast return of investment or a four-channel pipetting option delivering higher throughput in the same small amount of lab space
- Host connectivity
Freedom EVO configuration
- PosID™ 1D barcode scanner for primary tube, rack and carrier identification
- Flat 2D barcode scanner for identification of cryotubes
- Two- or four-channel Liquid Handling Arm™ for transferring samples from primary to destination tubes
- Manual barcode scanner for sample retrieval
Load and go sample transfer
Full traceability. The instrument matches the 1D barcodes of the primary tubes with the 2D barcoded secondary tubes and creates a worklist without the need to configure a host connection.
Host connectivity. The archiving information can be transferred to the LIS.
Clot identification. The system’s Freedom EVOware® software identifies clotted samples. If a clot is detected, the instrument pauses, notifies the user, and then proceeds according to the instructions given.
Standardization. Automation of sample aliquoting and archiving protocols increases throughput, frees up staff time, and removes the potential for human error that is inherent in tedious, time-consuming manual pipetting processes.
Operator safety. Primary tube racks can be loaded directly onto the workdeck, minimizing contact with potentially infectious samples. The workdeck is protected by a transparent front panel with electromagnetic locks controlled by the software. The system is completely closed, with an optional exhaust hood.
Simple aliquot identification. An external handheld barcode scanner is incorporated for straightforward scanning and identification of cryotube racks.
The information contained in the archive file record includes
- Cryotube rack barcode
- Sample barcode
- Aliquot barcode
- Position of the aliquot in the cryotube rack
- Date and time of aliquot creation
- Aliquot volume
- Original primary sample volume
Efficient separation of plasma or serum from the cellular layer
The user can define the transfer volume of serum or plasma for each run. Protocols for the separation of different sample volumes can be pre-programmed and selected by the user before the run start.
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Tab 04 / Software
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Introspect™ software
Introspect helps you keep track of what’s happening with your liquid handling instruments. You can also upload historical and archived instrument data, allowing you to study the past today and shape the future by making the most informed decisions possible.
Learn moreTecan Connect™
Take a break or plan your next experiment while monitoring your instrument on your smartphone with the Tecan Connect mobile app.
Connect is a cloud-based laboratory automation monitoring app that is designed to work with all Fluent and Freedom EVO® instruments.
Learn moreFreedom EVOlution™
Application-oriented software for pre-analytical laboratory tasks
The Freedom EVOlution software enables easy set-up of sophisticated pipetting procedures for pre-analytical sample distribution, assay preparation and archiving procedures that are processed on the Freedom EVO® Clinical.
Learn moreFluentControl™ – one great software, two powerful interfaces
FluentControl is designed to empower laboratories to build optimize, and maintain their own assays, without the need for computer programming expertise.
Users can simply drag and drop commands to create a protocol, and use the 3D editor to configure their worktable elements and labware.
Learn more
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Tab 05 / Literature
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Brochures
A dedicated platform designed for applications such as sample distribution, sample splitting and archiving. The instrument consists of a set of modules and options to deal with the routine tasks in clinical laboratories.
The Fluent Gx Automation Workstation is designed specifically to meet the needs of regulated laboratories, with all the advanced process security features required for applications in clinical, GMP and QC facilities.
The Freedom EVO series is one of the most popular and reliable systems on the market, with more than 5,000 systems installed worldwide. It offers a choice of worktable capacities, each with building block modularity that brings convenient scalability, proven liquid handling, easy-to-use robotics and advanced process control within reach of every laboratory scientist.
Tecan Journal Article
Laboratory services company synlab offers analysis of human, animal and environmental samples and, at its Augsburg site in Germany, it has chosen two Freedom EVO Clinical workstations in combination with the BEP® III system from Siemens to process an enormous throughput of EIAs to diagnose infectious diseases.
Laboratory services company synlab offers analysis of human, animal and environmental samples and, at its Augsburg site in Germany, it has chosen two Freedom EVO Clinical workstations in combination with the BEP® III system from Siemens to process an enormous throughput of EIAs to diagnose infectious diseases.
Virology testing at a molecular level is crucial for a fast and sensitive initial diagnosis, but its role doesn’t stop there. Clinicians frequently request retrospective analysis, sometimes as a means of monitoring drug response or identifying drug resistance, and also increasingly to understand the underlying mechanisms that lead to, for example, organ rejection. The San Raffaele Hospital in Milan has developed an automated archiving system that allows safe and accurate collection of clinical samples, as well as easy access and retrieval when further testing is required.
Related products
Related Topics
Freedom EVO Clinical are not for sale in the USA.